|
rs4713281
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
|
25604533 |
2015 |
|
rs11666543
|
|
|
0.710 |
GeneticVariation |
BEFREE |
We identified genetic susceptibility loci for Takayasu arteritis with a genome-wide level of significance in IL6 (rs2069837) (odds ratio [OR] 2.07, P = 6.70 × 10(-9)), RPS9/LILRB3 (rs11666543) (OR 1.65, P = 2.34 × 10(-8)), and an intergenic locus on chromosome 21q22 (rs2836878) (OR 1.79, P = 3.62 × 10(-10)).
|
25604533 |
2015 |
|
rs11666543
|
|
|
0.710 |
GeneticVariation |
GWASCAT |
We identified genetic susceptibility loci for Takayasu arteritis with a genome-wide level of significance in IL6 (rs2069837) (odds ratio [OR] 2.07, P = 6.70 × 10(-9)), RPS9/LILRB3 (rs11666543) (OR 1.65, P = 2.34 × 10(-8)), and an intergenic locus on chromosome 21q22 (rs2836878) (OR 1.79, P = 3.62 × 10(-10)).
|
25604533 |
2015 |
|
rs12980600
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
|
25604533 |
2015 |
|
rs2476601
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Totally, 181 patients with TA and 177 healthy controls are genotyped by PCR-RFLP method for the SNP rs2476601 (A/G) of PTPN22 gene.
|
18375974 |
2008 |
|
rs2476601
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This is the first report documenting an association between PTPN22 R620W and TA.
|
30470857 |
2019 |
|
rs33996649
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our data showed that the PTPN22 R620W polymorphism is a risk factor for TA (CC vs. CT: OR 4.3, p = 0.002, and C vs. T: OR 4.1, p = 0.003); however, the PTPN22 R263Q and - 1123G/C polymorphisms are not associated with this AD.
|
30470857 |
2019 |
|
rs2322599
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
|
30498034 |
2018 |
|
rs2736173
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
|
25604533 |
2015 |
|
rs6560480
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
|
25604533 |
2015 |
|
rs104895476
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A case of infantile Takayasu arteritis with a p.D382E NOD2 mutation: an unusual phenotype of Blau syndrome/early-onset sarcoidosis?
|
22821420 |
2013 |
|
rs28399987
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
|
25604533 |
2015 |
|
rs665268
|
|
|
0.020 |
GeneticVariation |
BEFREE |
MLX-Q139R mutation plays a crucial role in the pathogenesis of TAK through promoting inflammasome formation.
|
30354298 |
2018 |
|
rs665268
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Four single nucleotide polymorphisms (SNPs) those locate in the IL12B region (rs56167332), the MLX region (rs665268), the FCGR2A/FCGR3A locus (rs10919543), and the HLA-B/MICA locus (rs12524487), associated with TA in different population, were genotyped in 123 Chinese TA patients and 147 healthy controls from January 2013 to August 2014.
|
26996483 |
2016 |
|
rs114202986
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, rs3763288 and rs114202986 in MICA were negatively related to TA either as a whole or in any clinical features.
|
28261975 |
2018 |
|
rs3763288
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, rs3763288 and rs114202986 in MICA were negatively related to TA either as a whole or in any clinical features.
|
28261975 |
2018 |
|
rs12047961
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
|
25604533 |
2015 |
|
rs1713450
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
|
30498034 |
2018 |
|
rs1800795
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GG genotypes of rs1800795 in IL-6 was also associated with occurrence of tuberculosis in our patients with TA.
|
28438554 |
2018 |
|
rs2069837
|
|
|
0.720 |
GeneticVariation |
GWASCAT |
We identified genetic susceptibility loci for Takayasu arteritis with a genome-wide level of significance in IL6 (rs2069837) (odds ratio [OR] 2.07, P = 6.70 × 10(-9)), RPS9/LILRB3 (rs11666543) (OR 1.65, P = 2.34 × 10(-8)), and an intergenic locus on chromosome 21q22 (rs2836878) (OR 1.79, P = 3.62 × 10(-10)).
|
25604533 |
2015 |
|
rs2069837
|
|
|
0.720 |
GeneticVariation |
BEFREE |
Previous work has revealed a genetic association between Takayasu arteritis and a non-coding genetic variant in an enhancer region within <i>IL6</i> (rs2069837 A/G).
|
31315839 |
2019 |
|
rs2069837
|
|
|
0.720 |
GeneticVariation |
BEFREE |
We identified genetic susceptibility loci for Takayasu arteritis with a genome-wide level of significance in IL6 (rs2069837) (odds ratio [OR] 2.07, P = 6.70 × 10(-9)), RPS9/LILRB3 (rs11666543) (OR 1.65, P = 2.34 × 10(-8)), and an intergenic locus on chromosome 21q22 (rs2836878) (OR 1.79, P = 3.62 × 10(-10)).
|
25604533 |
2015 |
|
rs1004819
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, a trend for IL12A rs582054 and IL23R rs1004819 in association with the TA phenotype was detected.
|
26987707 |
2016 |
|
rs763780
|
|
|
0.010 |
GeneticVariation |
BEFREE |
G allele of rs763780 in IL-17F gene was protectively associated against susceptibility to TA.
|
28438554 |
2018 |
|
rs582054
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, a trend for IL12A rs582054 and IL23R rs1004819 in association with the TA phenotype was detected.
|
26987707 |
2016 |